The IEEE International Symposium on Biomedical Imaging 2021 (ISBI2021) was successfully held in the form of a virtual conference from April 13 to April 16, 2021. Professor Du Yuhui, who come from School of Computer and Information Technology, Shanxi University, contributed two papers — A New Hypergraph Clustering Method for Exploring Transdiagnostic Biotypes in MentalIllnesses: Application to Psychiatry and Psychotic Bipolar Disorder and A New Semi-supervised Non-negative Matrix FactorizationMethod for Brain Dynamic Functional Connectivity Analysis to this conference, and the first paper was chosen as an oral presentation.